Fa©t or F®iction study

About the study

The Fa©t or F®iction study investigates the potential of autologous, intraoperatively micronized fat tissue to reduce soft-tissue adhesions and enhance functional recovery following plate fixation of proximal phalanx fractures. During surgery, micronized fat tissue is applied directly around the fracture site and extensor apparatus before wound closure. The study aims to determine whether the addition of micronized fat can modulate the local inflammatory response, preserve tendon gliding and improve postoperative range of motion compared to standard fixation alone. Functional outcomes are evaluated using validated patient-reported outcome measures PROMs, objective hand function tests and high-resolution ultrasonography to assess tendon adhesion formation. The ultimate goal is to establish the regenerative and anti-fibrotic potential of micronized fat as an adjunct to fracture surgery in the hand.

Researchers

Principal investigator
E.P.A. van der Heijden, MD PhD
Coordinating researcher
Joris van Dongen, MD PhD

News

There is currently no news available.

Other studies